Epstein Bar Virus mnemonic - Microbiology mnemonics and tutorial

Epstein Bar virus [Einstein's Bar]

Double stranded DNA virus of the Herpes family [harp with two twisted strings]
Causative agent of infectious mononucleosis [mono gramophone, as opposed to stereo]
- Hepatosplenomegaly with fever [mono gramophone playing hot lively liver music] [enlarged organs and thermometer]
- Hairy leukoplakia - a white "hairy" growth in throat [in the throat of the old dusty gramophone]
- Neck and inguinal lymphadenopathy [beaded necklaces]
Spread by saliva and kissing ["Spitting and kissing contest"]
Infection induces production of characteristic heterophile antibodies [heterophile couples]
Infects B-cells but also causes T-cell dysfunction [Einstein in bee-shirt, laying drunk on the bar and spilling tea on his homework]
Infected cells tend to have increased activity of c-myc oncogene [see Mick(ey mouse)]
Associated with:
- Burkitt's B-cell lymphoma [homework drawing of a barking dog for which Einstein got a B (that's why he got drunk)]
  - Refractory to treatment [needle does not penetrate into the bar]
- Nasopharyngeal carcinoma [cancer (lobster) with big nose]
Virus gains entry into the cells via C3 complement receptor [see 3" sea in the bar]