Bruton's Agammaglobulinemia [Bee-rots-on the "lack of immunoglobulins"]

• Deficiency of immunoglobulins G, A, M, E [GAME Over]
• X-linked [X-crosshairs shot & killed the bee]
• Typical Presentation:
  • Recurrent otitis media/externa [sting piercing the ear]
  • Recurrent sinusitis [child with red inflamed sinuses]
  • Recurrent pneumonia [rotting lungs]

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Visual Mnemonic - Bruton's Agammaglobulinemia
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