Multiple Endocrine Neoplasia, Men I, Wermer, Men Iia, Sipple's, Men Iib mnemonic

Multiple Endocrine Neoplasia (MEN) [men cartoon characters]

MEN I
- PYGM mutation [short Pygmy man]
- Also known as Wermer syndrome [Pygmys live in warmer tropics, with 4 suns + a heat lamp!!!]
- Neoplasia of:
  - Pituitary [heat lamp]
  - Parathyroids [4 suns]
  - Pancreas [tropical island]
  - Carcinoids [car]
MEN IIA [the A-man]
- Medullary thyroid (c-cell) carcinoma [red medulla of thyroid at the top of the "A"]
- Parathyroid carcinoma [4 dots]
- Pheochromocytomas [medullas of adrenals forming the base of the "A"]
- Also known as Sipple's syndrome [the A is shaped like a steeple]
MEN IIB [last in sequence, looks like a bumble bee] a.k.a. type III
- Neuromas of the eye, buccal mucosa and GI mucosa [neurons]
- Fat lips
- Medullary thyroid (c-cell) carcinoma [red bow-tie ]
- Pheochromocytomas [Pockets shaped like the adrenals]
MEN IIA & MEN IIB have RETY mutation [they can't return to the tropical island]