Alkylating Agents [yellow DNA adducts]
- Mechlorethamine [Mechanics Lore and Ham Mine]
- Treatment of Hodgkin's lymphoma [ham was torn off from hog]
- Breast cancer
- Ovarian cancer [cracked egg]
- cyclophosphamide & ifosfamide [cycling phosphorus mite]
- Neuroblastoma [neuron blast]
- Breast cancer
- Ovarian cancer [cracked egg]
- non-Hodgkin's Lymphoma [NHL - national hockey league]
- nitrosoureas: Carmustine [car mustard tin] & lomustine [low mustard tin]
- Penetrate into CNS [tin cans sink into brain] and so are used for brain tumors
- Cisplatin & Carboplatin [sister plates and a full healthy breakfast]
- Ovarian tumors [egg]
- Testicular cancers [sperm cell]
- Lung cancers [Lung ham: part of a healthy breakfast]
- Bladder tumors (also eliminated via urine) [glass of "orange" juice]
- Side effects:
- Nephrotoxic [broken kidney]
- Hemolysis [half of RBC donut]
- Peripheral neuropathy [neuron crushed with blue periphery]
- Procarbazine & Dacarbazine [Da' Pro-Carbs Zine]
- Used to treat Hodgkin's lymphoma [eat hogs & carbs !!!]
- Side effects include rash, peripheral neuropathy and disulfiram-like effect [spotted rash on hog, squashed neuron]
- Inhibits MAO [Chinese Ruler, Mao ZeDong lays defeated]
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Visual Mnemonic - Alkylating Agents, Nitrosoureas: Mechlorethamine, Cyclophosphamide, Ifosfamide, Carmustine, Lomustine, Cisplatin, Carboplatin, Procarbazine, Dacarbazine
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