Fluoroquinolones: Ciprofloxacin, Enoxacin, Lomefloxacin, Norfloxacin, Trovafloxacin, Ofloxacin, Chlamydia, Haemophilus Influenzae, Tuberculosis, Neisseria, Legionella, Pseudomona Aeruginosa, Neisseria Meningitis mnemonic

Fluoroquinolones [fluorescent queen]

Target bacterial topoisomerase, inducing supercoiling of DNA [twisted hair strands]
Effective against:
- Chlamydia [cracked clam]
- Haemophilus influenzae [broken RBC lover]
- Tuberculosis [broken tuber]
- Neisseria [diplococcus]
- Legionella [legionnaire soldier in the crown]
Eliminated in urine [blonde hair strands melt into urine]
Magnesium inhibits absorption [magnet pulling away the fluorescent power]
Side effects:
- Produces crystalluria & nephrotoxic [broken kidney & crystal in urine]
- Induces phototoxicity [vicious sun]
Ciprofloxacin [sip red flow ox sine]
- Effective against:
  - Gram (-) bacteria [sipping red from bacterium]
  - Pseudomona aeruginosa [pseudo Mona Lisa]
  - Enterococcus [blocking entering coccus]
Enoxacin [equinox sine] and lomefloxacin [Lama ox sine]
- Effective against Haemophilus influenzae [RBC lover]
Norfloxacin [north ox sine]
- Effective against both Gram (+) and (-) bacteria [red & blue dots]
- Pseudomona aeruginosa [pseudo Mona Lisa]
Trovafloxacin [treasure trove ox sine]
Ofloxacin [big "O" ox sine]
- Good CNS penetration [brain]
- Treatment for Neisseria meningitis [diplococcus]
- Urinary tract/prostate infections [diplococcus, inflamed prostate]

Visual Mnemonic - Fluoroquinolones: Ciprofloxacin, Enoxacin, Lomefloxacin, Norfloxacin, Trovafloxacin, Ofloxacin, Chlamydia, Haemophilus Influenzae, Tuberculosis, Neisseria, Legionella, Pseudomona Aeruginosa, Neisseria Meningitis
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