Serotonin, Norepinephrine, Tyramine, Dopamine, Tranylcypromine, Phenelzine, Isocarboxazid mnemonic

MAO Inhibitors [Mao Tze Tung is defeated]

Monoamine oxidase (MAO) is a mitochondrial enzyme responsible for the degradation of catecholamines, decreasing their synaptic concentration
- MAO-A is selective for Serotonin, Norepinephrine, and Tyramine.
- MAO-A inhibition has antidepressant effects
- MAO-B is selective for Dopamine, and its inhibition yields antiparkinsonian effects.
MAO Inhibitors are used to treat:
- Depression [sad mask]
- Phobias [Insect]
- As anxiolytics [Axe lysis]
Tranylcypromine [running tea being sipped by a mine] acts as a reversible inhibitor
Phenelzine [Fan eel holding a magazine] is an irreversible inhibitor
Isocarboxazid [ISO 9000 (an industrial standard of high quality) rifle that has carboxy group with "O" serving as the eyepiece and "H" as the bullet] is an irreversible inhibitor [Kills MAO enzyme]
MAOI cause blurry vision as a side effect [blurry eye]