Neuromuscular Blockers, Nicotinic Blockers: Curare, Acetylcholine, Doxacurium, Mivacurium, Pancuronium, Tubocurarine, Metocurine, Atracurium, Rocuronium, Vecuronium, Succinylcholine, Dantrolene mnemonic

Neuromuscular Blockers & Nicotinic Blockers [block the cigarette]

Derivatives of curare, a poison used in arrow tips [arrows]
- Block acetylcholine [acetylene torch]
- Most are excreted by the kidneys [kidney is inhaling the arrows]
  - doxacurium [dog curare]
  - Mivacurium ["me vacuum" curare]
    - Fast onset and resolution of action [red speed streaks]
  - Pancuronium [pan curare arrow]
    - Causes tachycardia [running heart]
  - tubocurarine [tube arrow]
    - Lowers blood pressure [low BP indicator]
  - metocurine [me too curare arrow]
- Atracurium [a track curare arrow]
  - Degraded by plasma enzymes [a track arrow leaves the scene omitting the kidney and liver]
  - Fast acting [red speed streaks]
- Metabolized by the liver [eaten by the liver]
  - rocuronium [row curare arrow]
    - Fast acting [red speed streaks]
  - vecuronium [We are a V-arrow]
Succinylcholine [sucking coal (sucking so hard that the face turned blue)]
- Stimulates the nicotinic receptor [sucking on a cigarette makes it burn more intensely]
- Causes prolonged depolarization marked first by muscle fasciculations followed by flaccid paralysis
- Causes influx of sodium into the cell [Na arrows]
Miscellaneous: dantrolene [ant rolling (around sarcoplasmic reticulum)]
- Blocks release of Calcium [ant rolling traps the California surfer dude]
- Used in treatment of malignant hyperthermia

Visual Mnemonic - Neuromuscular Blockers, Nicotinic Blockers: Curare, Acetylcholine, Doxacurium, Mivacurium, Pancuronium, Tubocurarine, Metocurine, Atracurium, Rocuronium, Vecuronium, Succinylcholine, Dantrolene
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